Michael Cory


Michael Cory
  • 2015 Beckman Scholar
  • Synthetic Biology Fellow, Harvard Medical School (starting fall 2023)

Biography

Michael is from Wichita, Kansas, where he spent his junior and senior high school years at the Kansas Academy of Mathematics and Science at Fort Hays State University. He graduated from the University of Kansas in May 2017 with a B.S. degree in Biochemistry, earning Departmental Honors.  While at KU, Michael joined the laboratory of Dr. John Karanicolas, who became his Beckman Scholars Program mentor.  His project in the Karanicolas group centered on identifying small molecules that can rescue the activity of the lac repressor in E. coli in the context of special loss-of-function mutations, through a combined computational and experimental approach. After graduation from KU, Michael earned a Ph.D. in biochemistry from the University of Pennsylvania. He is currently a Synthetic Biology Fellow at Harvard Medical School.

Education

B.S. in Biochemistry, University of Kansas, 2017, Lawrence, KS
Departmental Honors
Ph.D. in Biochemistry, University of Pennsylvania, 2023, Philadelphia, PA

Selected Publications

From University of Kansas

Budiardjo, S.J.; Licknack, T.J.; Cory, M.B.; Kapros, D.; Roy, A.; Lovell, S.; Douglas, J.; Karanicolas, J. "Full and Partial Agonism of a Designed Enzyme Switch" ACS Synthetic Biology 2016, 5, 1475-1484.

Patent: Bellacosa A., Karanicolas J., Yen T.J., Cory M., Parry C., Prasad R. Methods of treating cancer. International Publication Number: WO/2022/047288A9

 

From University of Pennsylvania

Hostetler, Z.M.; Cory, M.B.; Jones, C.M.; Petersson, E.J.; Kohli, R.M. "The Kinetic and Molecular Basis for the Interaction of LexA and Activated RecA Revealed by a Fluorescent Amino Acid Probe" ACS Chem. Biol. 2020, 15(5), 1127-1133. 

Eilers, G.; Gupta, K.; Allen, A.; Zhou, J.; Hwant, Y.; Cory, M.B.; Bushman, F.D.; Van Duyne, G. "Influence of the amino-terminal sequence no the structure and function of HIV integrase" Retrovirology, 2020, 17(1), 1-16. 

Jaramillo, A.V.C.; Cory, M.B.; Li, Allen; Kohli, R.M.; Wuest, W.M. "Exploration of inhibitors of the bacterial LexA repressor-protease" Bioorg. Med. Chem. Lett. 2022, 65, 128702 (https://doi.org/10.1016/j.bmcl.2022.128702)

Cory, M.B.; Hostetler, Z.M.; Kohli, R.M. "Kinetic Dissection of Macromolecular Complex Formation with Minimally Perturbing Fluorescent Probes" Methods Enzymol. 2022, 664, 151-171.

Selected Presentations

Gulf Coast Undergraduate Research Symposium; Rice University, Houston, TX; "Full and Partial Agonism of a Designed Enzyme Switch" October 2016 (talk )

Beckman Symposium, Irvine, CA. "Full and Partial Agonism of a Designed Enzyme Switch" August 2016 (Poster)

KU Biology Honors Symposium, University of Kansas, Lawrence, KS; "Full and Partial Agonism of a Designed Enzyme Switch" April 2017 (Poster)

Awards & Honors

Graduation with Honors in Biology

Induction into Phi Beta Kappa

Grants & Other Funded Activity

Re-appointed to T32 training grant in Microbial Genetics and Pathogenesis for 2020-2021 cycle