Departments of Chemistry & Molecular Biosciences

Kathryn Brewer

2016 Beckman Program Scholar
Primary office:

Kathryn Brewer is from Overland Park, Kansas, where she attended Blue Valley West High School. She is majoring in chemistry with a concentration in biochemistry.  The project she is pursuing under the mentorship of Dr. Audrey Lamb focuses on understanding an iron uptake system in Pseudomonas aeruginosa, which involves the synthesis of iron-chelating molecules called siderophores. In this project, one of the enzymes in the biosynthetic pathway of the siderophore called pyoverdin is being studied. This enzyme requires post-translational modification prior to becoming catalytically active.  A fluorescent probe has been synthesized that will allow this modification to be detected, and modification tests are currently underway. Once modification has been successfully demonstrated, kinetic studies and crystallization efforts of the protein will begin.

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